Information: Infusion.. 000 Civox 200 mg / 100 ml
Therapeutic action
– Fluoroquinolone antibacterial
Indications
– Shigellosis, typhoid fever, cutaneous anthrax
– Uncomplicated acute cystitis in non-pregnant women or in the event of previous treatment failure, acute prostatitis, uncomplicated acute pyelonephritis, chancroid
Presentation
– 250 mg and 500 mg tablets
– 250 mg/5 ml granules and solvent for oral suspension
Dosage
– Shigellosis, typhoid fever, cutaneous anthrax
Child over 1 month: 30 mg/kg/day in 2 divided doses (max. 1 g/day) Adult: 1 g/day in 2 divided doses
Age Weight 250 mg/5 ml susp. 250 mg tablet 500 mg tablet
1 to < 3 months 4 to < 6 kg 1.5 ml x 2 - -
3 to < 7 months 6 to < 8 kg 2 ml x 2 - -
7 months to < 2 years 8 to < 12 kg 2.5 ml x 2 - -
2 to < 3 years 12 to < 15 kg 4 ml x 2 - -
3 to < 8 years 15 to < 26 kg 5 ml x 2 1 tab x 2 -
8 to < 11 years 26 to < 36 kg 8 ml x 2 - -
≥ 11 years and adult ≥ 36 kg - 2 tab x 2 1 tab x 2
– Uncomplicated acute cystitis in non-pregnant women
Adult: 500 mg/day in 2 divided doses
– Acute cystitis (in the event of recurrence or treatment failure), acute prostatitis, chancroid
Adult: 1 g/day in 2 divided doses
– Uncomplicated acute pyelonephritis
Adult: 1 to 1.5 g/day in 2 to 3 divided doses
Duration
– Shigellosis, uncomplicated cystitis, chancroid: 3 days; cystitis (in the event of recurrence or treatment failure): 5 days; typhoid fever: 5 to 7 days; pyelonephritis: 7 days; cutaneous anthrax: 7 to 10 days; prostatitis: 28 days
Contra-indications, adverse effects, precautions
– Do not administer to patients with history of allergy or tendinitis due to fluoroquinolones.
– Administer with caution to epileptic patients (risk of seizures).
– Reduce the dose by half in patients with renal impairment.
– May cause: gastrointestinal disturbances, neurological disorders (headache, dizziness, confusion, hallucinations, seizures), allergic reaction, peripheral neuropathy, photosensitivity (protect skin from sun exposure), arthralgia, myalgia, tendon damage (especially Achilles tendinitis), QT interval prolongation, hypo/hyperglycaemia, haemolytic anaemia in patients with G6PD deficiency. In the event of allergic reaction, severe neurological disorders, peripheral neuropathy or tendinitis, stop treatment immediately.
– Avoid combination with drugs that prolong the QT interval (amiodarone, chloroquine, co-artemether, fluconazole, haloperidol, mefloquine, ondansetron, pentamidine, quinine, etc.).
– Monitor patients taking glibenclamide (risk of hypoglycaemia).
– Do not administer simultaneously with antacids (aluminium or magnesium hydroxide, etc.), iron salts, calcium. Administer 2 hours apart.
– Drink a lot of liquid during treatment (risk of crystalluria).
– Pregnancy: reserved for severe infections, when there is no therapeutic alternative.
– Breast-feeding: no contra-indication
Remarks
– Storage: below 25°C –
http://www.popular-pharma.com/products/300
https://medlineplus.gov/druginfo/meds/a688016.html
https://en.wikipedia.org/wiki/Ciprofloxacin